Generalized Gibbs priors based positron emission tomography reconstruction
نویسندگان
چکیده
Bayesian methods have been widely applied to the ill-posed problem of image reconstruction. Typically the prior information of the objective image is needed to produce reasonable reconstructions. In this paper, we propose a novel generalized Gibbs prior (GG-Prior), which exploits the basic affinity structure information in an image. The motivation for using the GG-Prior is that it has been shown to suppress noise effectively while capturing sharp edges without oscillations. This feature makes it particularly attractive for those applications of Positron Emission Tomographic (PET) where the objective is to identify the shape of objects (e.g.tumors) that are distinguished from the background by sharp edges. We show that the standard paraboloidal surrogate coordinate ascent (PSCA) algorithm can be modified to incorporate the GG-Prior using a local linearized scheme in each iteration process. The proposed GG-Prior MAP reconstruction algorithm based on PSCA algorithm has been tested on simulated, real phantom data. Comparisons the GG-Prior model with other existing prior model clearly demonstrate that the proposed GG-Prior performs better in lowering the noise, and preserving the edge and detail in the image.
منابع مشابه
Comparison of Lesion Detection and Quantification in MAP Reconstruction with Gaussian and Non-Gaussian Priors
Statistical image reconstruction methods based on maximum a posteriori (MAP) principle have been developed for emission tomography. The prior distribution of the unknown image plays an important role in MAP reconstruction. The most commonly used prior are Gaussian priors, whose logarithm has a quadratic form. Gaussian priors are relatively easy to analyze. It has been shown that the effect of a...
متن کاملValidation of New Gibbs Priors for Bayesian Tomographic Reconstruction Using Physically Acquired Data
The variety of Bayesian MAP approaches to tomography proposed in recent years can both stabilize reconstructions and lead to improved bias and variance. In our previous work [1, 2], we showed that the thin-plate (TP) prior, which is less sensitive to variations in first spatial derivatives than the conventional membrane (MM) prior, yields improved reconstructions in the sense of low bias. In sp...
متن کاملDetection of Alzheimer\\\\\\\'s Disease using Multitracer Positron Emission Tomography Imaging
Alzheimer's disease is characterized by impaired glucose metabolism and demonstration of amyloid plaques. Individual positron emission tomography tracers may reveal specific signs of pathology that is not readily apparent on inspection of another one. Combination of multitracer positron emission tomography imaging yields promising results. In this paper, 57 Alzheimer's disease neuroimaging ini...
متن کاملAutomated estimation of the parameters of Gibbs priors to be used in binary tomography
Image modeling using Gibbs priors was previously shown, based on experiments, to be e1ective in image reconstruction problems. This motivated us to evaluate three methods for estimating the priors. Two of them accurately recover the parameters of the priors; however, all of them are useful for binary tomography. This is demonstrated by two sets of experiments: in one the images are from a Gibbs...
متن کاملOptimized Image Reconstruction for Emission Tomography Using Ordered Subsets, Median Root Prior and a Web-based Interface
The main objective of this work is the development and evaluation of iterative image reconstruction (IIR) methods for multitracer dynamic positron emission tomography (mdPET) studies. The ordered subsets (OS) technique applied for the acceleration of the maximum likelihood expectation maximization (ML-EM) IIR algorithm, is here extended to include the weighted-least squares (WLS), image space r...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Computers in biology and medicine
دوره 40 6 شماره
صفحات -
تاریخ انتشار 2009